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Molecular Dynamics Simulations of E. coli MsbA Transmembrane Domain: Formation of a Semipore Structure
The human P-glycoprotein (MDR1/P-gp) is an ATP-binding cassette (ABC) transporter involved in cellular response to chemical stress and failures of anticancer chemotherapy. In the absence of a high-resolution structure for P-gp, we were interested in the closest P-gp homolog for which a crystal struc...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1562368/ https://ncbi.nlm.nih.gov/pubmed/16782794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.084020 |
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