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Specific Inhibition of Bovine Viral Diarrhea Virus Replicase

Compound-1453 was identified and characterized as a specific inhibitor of bovine viral diarrhea virus (BVDV). The concentration of compound-1453 which results in 50% protection from virus-induced cytopathic effect is ∼2.2 μM, with a therapeutic index of 60, and it is not active against a panel of RN...

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Main Authors: Sun, Jin-Hua, Lemm, Julie A., O'Boyle II, Donald R., Racela, Jason, Colonno, Richard, Gao, Min
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC156199/
https://ncbi.nlm.nih.gov/pubmed/12767995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.12.6753-6760.2003
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