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Progressive Truncations C Terminal to the Membrane-Spanning Domain of Simian Immunodeficiency Virus Env Reduce Fusogenicity and Increase Concentration Dependence of Env for Fusion

The simian immunodeficiency virus (SIV) transmembrane (TM) protein, gp41, has multiple functions, which include anchoring the glycoprotein complex in the lipid envelope of the virus and mediating fusion of the virus and host cell membranes. Recently, a series of mutants of the SIVmac239 TM protein t...

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Hlavní autoři: Lin, Xiaoxu, Derdeyn, Cynthia A., Blumenthal, Robert, West, John, Hunter, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC156184/
https://ncbi.nlm.nih.gov/pubmed/12768026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.12.7067-7077.2003
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