Targeting of the Human Immunodeficiency Virus Type 1 Envelope to the trans-Golgi Network through Binding to TIP47 Is Required for Env Incorporation into Virions and Infectivity

Here, we report that human immunodeficiency virus type 1 (HIV-1) Env glycoprotein is located mainly in the trans-Golgi network (TGN) due to determinants present in the cytoplasmic domain of the transmembrane gp41 glycoprotein (TMgp41). Internalization assays demonstrated that Env present at the cell...

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Pubblicato in:	J Virol
Autori principali:	Blot, Guillaume, Janvier, Katy, Le Panse, Sophie, Benarous, Richard, Berlioz-Torrent, Clarisse
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Virus-Cell Interactions
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156179/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12768012/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.12.6931-6945.2003
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