Monocytes Treated with Human Immunodeficiency Virus Tat Kill Uninfected CD4(+) Cells by a Tumor Necrosis Factor-Related Apoptosis-Induced Ligand-Mediated Mechanism

The human immunodeficiency virus (HIV) Tat protein has a critical role in viral transcription, but this study focuses on its additional role as an extracellular effector of lymphocyte cell death. It is well known that Tat induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL) in peri...

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Detalhes bibliográficos
Main Authors: Yang, Yida, Tikhonov, Ilia, Ruckwardt, Tracy J., Djavani, Mahmoud, Zapata, Juan Carlos, Pauza, C. David, Salvato, Maria S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156176/
https://ncbi.nlm.nih.gov/pubmed/12767990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.12.6700-6708.2003
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