Human Immunodeficiency Virus Type 1 Envelope-Mediated Neuronal Death: Uncoupling of Viral Replication and Neurotoxicity

Although brain tissue from patients with human immunodeficiency virus (HIV) and/or AIDS is consistently infected by HIV type 1 (HIV-1), only 20 to 30% of patients exhibit clinical or neuropathological evidence of brain injury. Extensive HIV-1 sequence diversity is present in the brain, which may acc...

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Bibliographic Details
Main Authors: Zhang, Kunyan, Rana, Farazana, Silva, Claudia, Ethier, Julie, Wehrly, Kathy, Chesebro, Bruce, Power, Christopher
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC156161/
https://ncbi.nlm.nih.gov/pubmed/12768009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.12.6899-6912.2003
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