PML Colocalizes with and Stabilizes the DNA Damage Response Protein TopBP1

The PML tumor suppressor gene is consistently disrupted by t(15;17) in patients with acute promyelocytic leukemia. Promyelocytic leukemia protein (PML) is a multifunctional protein that plays essential roles in cell growth regulation, apoptosis, transcriptional regulation, and genome stability. Our...

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Bibliographic Details
Main Authors: Xu, Zhi-Xiang, Timanova-Atanasova, Anna, Zhao, Rui-Xun, Chang, Kun-Sang
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC156140/
https://ncbi.nlm.nih.gov/pubmed/12773567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.12.4247-4256.2003
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