TAF10 (TAF(II)30) Is Necessary for TFIID Stability and Early Embryogenesis in Mice

TAF10 (formerly TAF(II)30), is a component of TFIID and the TATA box-binding protein (TBP)-free TAF-containing complexes (TFTC/PCAF/STAGA). To investigate the physiological function of TAF10, we disrupted its gene in mice by using a Cre recombinase/LoxP strategy. Interestingly, no TAF10(−/−) animals...

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Hlavní autoři: Mohan II, William S., Scheer, Elisabeth, Wendling, Olivia, Metzger, Daniel, Tora, Làszlò
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Mammalian Genetic Models with Minimal or Complex Phenotypes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC156135/
https://ncbi.nlm.nih.gov/pubmed/12773572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.12.4307-4318.2003
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