Heart and Liver Defects and Reduced Transforming Growth Factor β2 Sensitivity in Transforming Growth Factor β Type III Receptor-Deficient Embryos

The type III transforming growth factor β (TGFβ) receptor (TβRIII) binds both TGFβ and inhibin with high affinity and modulates the association of these ligands with their signaling receptors. However, the significance of TβRIII signaling in vivo is not known. In this study, we have sought to determ...

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Detalhes bibliográficos
Main Authors: Stenvers, Kaye L., Tursky, Melinda L., Harder, Kenneth W., Kountouri, Nicole, Amatayakul-Chantler, Supavadee, Grail, Dianne, Small, Clayton, Weinberg, Robert A., Sizeland, Andrew M., Zhu, Hong-Jian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156130/
https://ncbi.nlm.nih.gov/pubmed/12773577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.12.4371-4385.2003
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