Mature CD8(+) T lymphocyte response to viral infection during fetal life

Immunization of newborns against viral infections may be hampered by ineffective CD8(+) T cell responses. To characterize the function of CD8(+) T lymphocytes in early life, we studied newborns with congenital human cytomegalovirus (HCMV) infection. We demonstrate that HCMV infection in utero leads...

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Detalhes bibliográficos
Main Authors: Marchant, Arnaud, Appay, Victor, van der Sande, Marianne, Dulphy, Nicolas, Liesnard, Corinne, Kidd, Michael, Kaye, Steve, Ojuola, Olubukola, Gillespie, Geraldine M.A., Vargas Cuero, Ana L., Cerundolo, Vincenzo, Callan, Margaret, McAdam, Keith P.W.J., Rowland-Jones, Sarah L., Donner, Catherine, McMichael, Andrew J., Whittle, Hilton
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156108/
https://ncbi.nlm.nih.gov/pubmed/12782677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317470
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