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Cdc2-mediated phosphorylation of Kid controls its distribution to spindle and chromosomes
The chromokinesin Kid is important in chromosome alignment at the metaphase plate. Here, we report that Kid function is regulated by phosphorylation. We identify Ser427 and Thr463 as M phase-specific phosphorylation sites and Cdc2–cyclin B as a Thr463 kinase. Kid with a Thr463 to alanine mutation fa...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC156080/ https://ncbi.nlm.nih.gov/pubmed/12727876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg208 |
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