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Interplay between Ino80 and Swr1 chromatin remodeling enzymes regulates cell cycle checkpoint adaptationin response to DNA damage

Ino80 and Swr1 are ATP-dependent chromatin remodeling enzymes that have been implicated in DNA repair. Here we show that Ino80 is required for cell cycle checkpoint adaptation in response to a persistent DNA double-strand break (DSB). The failure of cells lacking Ino80 to escape checkpoint arrest co...

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Bibliografiske detaljer
Main Authors: Papamichos-Chronakis, Manolis, Krebs, Jocelyn E., Peterson, Craig L.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560417/
https://ncbi.nlm.nih.gov/pubmed/16951256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1440206
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