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CXCR2 ligands and G-CSF mediate PKCα-induced intraepidermal inflammation
Transgenic mice overexpressing PKCα in the epidermis (K5-PKCα mice) exhibit an inducible severe intraepidermal neutrophilic inflammation and systemic neutrophilia when PKCα is activated by topical 12-O-tetradecanoylphorbol-13-acetate (TPA). This inducible model of cutaneous inflammation was used to...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1560349/ https://ncbi.nlm.nih.gov/pubmed/16964312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27514 |
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