Epidemic dynamics and antigenic evolution in a single season of influenza A

We use a mathematical model to study the evolution of influenza A during the epidemic dynamics of a single season. Classifying strains by their distance from the epidemic-originating strain, we show that neutral mutation yields a constant rate of antigenic evolution, even in the presence of epidemic...

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Bibliographic Details
Main Authors: Boni, Maciej F, Gog, Julia R, Andreasen, Viggo, Feldman, Marcus W
Format: Artigo
Language:Inglês
Published: The Royal Society 2006
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560306/
https://ncbi.nlm.nih.gov/pubmed/16777717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2006.3466
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