Assessment of whole genome amplification-induced bias through high-throughput, massively parallel whole genome sequencing

BACKGROUND: Whole genome amplification is an increasingly common technique through which minute amounts of DNA can be multiplied to generate quantities suitable for genetic testing and analysis. Questions of amplification-induced error and template bias generated by these methods have previously bee...

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Detalhes bibliográficos
Main Authors: Pinard, Robert, de Winter, Alex, Sarkis, Gary J, Gerstein, Mark B, Tartaro, Karrie R, Plant, Ramona N, Egholm, Michael, Rothberg, Jonathan M, Leamon, John H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560136/
https://ncbi.nlm.nih.gov/pubmed/16928277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-7-216
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