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Temperature- and Length-Dependent Energetics of Formation for Polyalanine Helices in Water: Assignment of w(Ala)(n,T) and Temperature-Dependent CD Ellipticity Standards

Length-dependent helical propensities w(Ala)(n,T) at T = 10, 25, and 60 °C are assigned from t/c values and NMR (13)C chemical shifts for series 1 peptides TrpLys(m)Inp(2)(t)Leu–Ala(n)(t)LeuInp(2)Lys(m)NH(2), n = 15, 19, and 25, m = 5, in water. Van’t Hoff analysis of w(Ala)(n,T) show that α-helix f...

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Detalhes bibliográficos
Main Authors: Job, Gabriel E., Kennedy, Robert J., Heitmann, Björn, Miller, Justin S., Walker, Sharon M., Kemp*, Daniel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560101/
https://ncbi.nlm.nih.gov/pubmed/16787087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja060094y
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