Cellular Prion Protein and Caveolin-1 Interaction in a Neuronal Cell Line Precedes Fyn/Erk 1/2 Signal Transduction

It has been reported that cellular prion protein (PrPc) is enriched in caveolae or caveolae-like domains with caveolin-1 (Cav-1) participating to signal transduction events by Fyn kinase recruitment. By using the Glutathione-S-transferase (GST)-fusion proteins assay, we observed that PrPc strongly i...

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Main Authors: Toni, Mattia, Spisni, Enzo, Griffoni, Cristiana, Santi, Spartaco, Riccio, Massimo, Lenaz, Patrizia, Tomasi, Vittorio
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559926/
https://ncbi.nlm.nih.gov/pubmed/17489019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/JBB/2006/69469
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