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Centromeric chromatin pliability and memory at a human neocentromere

We show that Trichostatin A (TSA)-induced partial histone hyperacetylation causes a unidirectional shift in the position of a previously defined binding domain for the centromere-specific histone H3 homologue CENP-A at a human neocentromere. The shift of ∼320 kb is fully reversible when TSA is remov...

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Autors principals: Craig, Jeffrey M., Wong, Lee H., Lo, Anthony W.I., Earle, Elizabeth, Choo, K.H.Andy
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC155990/
https://ncbi.nlm.nih.gov/pubmed/12743043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg232
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