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Biosynthesis of Costunolide, Dihydrocostunolide, and Leucodin. Demonstration of Cytochrome P450-Catalyzed Formation of the Lactone Ring Present in Sesquiterpene Lactones of Chicory

Chicory (Cichorium intybus) is known to contain guaianolides, eudesmanolides, and germacranolides. These sesquiterpene lactones are postulated to originate from a common germacranolide, namely (+)-costunolide. Whereas a pathway for the formation of germacra-1(10),4,11(13)-trien-12-oic acid from farn...

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Detalhes bibliográficos
Main Authors: de Kraker, Jan-Willem, Franssen, Maurice C.R., Joerink, Maaike, de Groot, Aede, Bouwmeester, Harro J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Plant Physiologists 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155889/
https://ncbi.nlm.nih.gov/pubmed/12011356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1104/pp.010957
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