Biochemical Characterization of β-Lactamases Bla1 and Bla2 from Bacillus anthracis

The Sterne and Ames strains of Bacillus anthracis carry chromosomal genes bla1 and bla2, which confer β-lactam resistance when expressed in Escherichia coli. MIC measurements and steady-state kinetic analyses indicate that Bla1 possesses penicillinase activity while Bla2 possesses penicillinase, cep...

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Main Authors: Materon, Isabel C., Queenan, Anne Marie, Koehler, Theresa M., Bush, Karen, Palzkill, Timothy
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2003
主題:
Mechanisms of Resistance
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC155864/
https://ncbi.nlm.nih.gov/pubmed/12760895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.6.2040-2042.2003
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