Genes regulated by estrogen in breast tumor cells in vitro are similarly regulated in vivo in tumor xenografts and human breast tumors

BACKGROUND: Estrogen plays a central role in breast cancer pathogenesis. Although many studies have characterized the estrogen regulation of genes using in vitro cell culture models by global mRNA expression profiling, it is not clear whether these genes are similarly regulated in vivo or how they m...

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Detalhes bibliográficos
Main Authors: Creighton, Chad J, Cordero, Kevin E, Larios, Jose M, Miller, Rebecca S, Johnson, Michael D, Chinnaiyan, Arul M, Lippman, Marc E, Rae, James M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557996/
https://ncbi.nlm.nih.gov/pubmed/16606439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2006-7-4-r28
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