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Unusual misregulation of RNA splicing caused by insertion of a transposable element into the T (Brachyury) locus

BACKGROUND: The T(Wis )mutant allele of the Brachyury, or T, gene was created by insertion of an endogenous retrovirus-like early transposon (ETn) element into the exon 7 splice donor consensus sequence of the 8 exon T locus. While the developmental consequences of this disruption have been well cha...

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Main Authors: Goldin, Sarah N, Papaioannou, Virginia E
格式: Artigo
語言:Inglês
出版: BioMed Central 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC155784/
https://ncbi.nlm.nih.gov/pubmed/12702217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-4-14
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