STAC: A method for testing the significance of DNA copy number aberrations across multiple array-CGH experiments

Regions of gain and loss of genomic DNA occur in many cancers and can drive the genesis and progression of disease. These copy number aberrations (CNAs) can be detected at high resolution by using microarray-based techniques. However, robust statistical approaches are needed to identify nonrandom ga...

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Autors principals: Diskin, Sharon J., Eck, Thomas, Greshock, Joel, Mosse, Yael P., Naylor, Tara, Stoeckert, Christian J., Weber, Barbara L., Maris, John M., Grant, Gregory R.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2006
Matèries:
Methods
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557772/
https://ncbi.nlm.nih.gov/pubmed/16899652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5076506
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