STAC: A method for testing the significance of DNA copy number aberrations across multiple array-CGH experiments

Regions of gain and loss of genomic DNA occur in many cancers and can drive the genesis and progression of disease. These copy number aberrations (CNAs) can be detected at high resolution by using microarray-based techniques. However, robust statistical approaches are needed to identify nonrandom ga...

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Bibliographic Details
Main Authors: Diskin, Sharon J., Eck, Thomas, Greshock, Joel, Mosse, Yael P., Naylor, Tara, Stoeckert, Christian J., Weber, Barbara L., Maris, John M., Grant, Gregory R.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2006
Subjects:
Methods
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557772/
https://ncbi.nlm.nih.gov/pubmed/16899652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5076506
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