Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026]

INTRODUCTION: Experimental and clinical data show that the oral bisphosphonate clodronate (Bonefos(®)) can inhibit tumor-induced osteoclastic bone resorption. This randomized, double-blind, placebo-controlled, multicenter trial was designed to determine if the addition of oral clodronate to standard...

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Detalhes bibliográficos
Main Authors: Powles, Trevor, Paterson, Alexander, McCloskey, Eugene, Schein, Phil, Scheffler, Bobbi, Tidy, Alwynne, Ashley, Sue, Smith, Ian, Ottestad, Lars, Kanis, John
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557723/
https://ncbi.nlm.nih.gov/pubmed/16542503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1384
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