Tumor-specific expression of αvβ3 integrin promotes spontaneous metastasis of breast cancer to bone

INTRODUCTION: Studies in xenograft models and experimental models of metastasis have implicated several β3 integrin-expressing cell populations, including endothelium, platelets and osteoclasts, in breast tumor progression. Since orthotopic human xenograft models of breast cancer are poorly metastat...

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Autors principals: Sloan, Erica K, Pouliot, Normand, Stanley, Kym L, Chia, Jenny, Moseley, Jane M, Hards, Daphne K, Anderson, Robin L
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2006
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557720/
https://ncbi.nlm.nih.gov/pubmed/16608535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1398
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