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U1-like snRNAs lacking complementarity to canonical 5′ splice sites

We have detected a surprising heterogeneity among human spliceosomal U1 small nuclear RNA (snRNA). Most interestingly, we have identified three U1 snRNA variants that lack complementarity to the canonical 5′ splice site (5′SS) GU dinucleotide. Furthermore, we have observed heterogeneity among the id...

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Detalhes bibliográficos
Main Authors: Kyriakopoulou, Christina, Larsson, Pontus, Liu, Lei, Schuster, Jens, Söderbom, Fredrik, A. Kirsebom, Leif, Virtanen, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557696/
https://ncbi.nlm.nih.gov/pubmed/16829670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.26506
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