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Bistability of Cell-Matrix Adhesions Resulting from Nonlinear Receptor-Ligand Dynamics

Bistability is a major mechanism for cellular decision making and usually results from positive feedback in biochemical control systems. Here we show theoretically that bistability between unbound and bound states of adhesion clusters results from positive feedback mediated by structural rather than...

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Bibliografiske detaljer
Main Authors: Erdmann, Thorsten, Schwarz, Ulrich S.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557548/
https://ncbi.nlm.nih.gov/pubmed/16829560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.090209
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