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Selection of suitable reference genes for accurate normalization of gene expression profile studies in non-small cell lung cancer

BACKGROUND: In real-time RT quantitative PCR (qPCR) the accuracy of normalized data is highly dependent on the reliability of the reference genes (RGs). Failure to use an appropriate control gene for normalization of qPCR data may result in biased gene expression profiles, as well as low precision,...

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Hlavní autoři: Silvia, Saviozzi, Francesca, Cordero, Marco, Lo Iacono, Silvia, Novello, Giorgio V, Scagliotti, Raffaele, Calogero A
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557528/
https://ncbi.nlm.nih.gov/pubmed/16872493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-200
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