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Efficient generation of double heterologous promoter controlled oncolytic adenovirus vectors by a single homologous recombination step in Escherichia coli

BACKGROUND: Oncolytic adenoviruses are promising agents for the multimodal treatment of cancer. However, tumor-selectivity is crucial for their applicability in patients. Recent studies by several groups demonstrated that oncolytic adenoviruses with tumor-/tissue-specific expression of the E1 and E4...

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Bibliografiset tiedot
Päätekijät: Hoffmann, Dennis, Wildner, Oliver
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557486/
https://ncbi.nlm.nih.gov/pubmed/16887042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-6-36
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