Analysis of the OspE Determinants Involved in Binding of Factor H and OspE-Targeting Antibodies Elicited during Borrelia burgdorferi Infection in Mice

Immune evasion by Lyme spirochetes is a multifactorial process involving numerous mechanisms. The OspE protein family undergoes antigenic variation during infection and binds factor H (fH) and possibly FHL-1/reconectin. In Borrelia burgdorferi B31MI, the OspE family consists of three paralogs: BBL39...

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Detalhes bibliográficos
Main Authors: Metts, Michael S., McDowell, John V., Theisen, Michael, Hansen, Paul Robert, Marconi, Richard Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155734/
https://ncbi.nlm.nih.gov/pubmed/12761144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.6.3587-3596.2003
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