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Chemokine Receptor CCR2 Is Not Essential for the Development of Experimental Cerebral Malaria

Infection with Plasmodium berghei ANKA induces cerebral malaria in susceptible mice. Brain-sequestered CD8(+) T cells are responsible for this pathology. We have evaluated the role of CCR2, a chemokine receptor expressed on CD8(+) T cells. Infected CCR2-deficient mice were as susceptible to cerebral...

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Dettagli Bibliografici
Autori principali: Belnoue, Elodie, Costa, Fabio T. M., Vigário, Ana M., Voza, Tatiana, Gonnet, Françoise, Landau, Irène, van Rooijen, Nico, Mack, Matthias, Kuziel, William A., Rénia, Laurent
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC155705/
https://ncbi.nlm.nih.gov/pubmed/12761155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.6.3648-3651.2003
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