BLOC-1 Complex Deficiency Alters the Targeting of Adaptor Protein Complex-3 Cargoes

Mutational analyses have revealed many genes that are required for proper biogenesis of lysosomes and lysosome-related organelles. The proteins encoded by these genes assemble into five distinct complexes (AP-3, BLOC-1-3, and HOPS) that either sort membrane proteins or interact with SNAREs. Several...

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Main Authors: Salazar, G., Craige, B., Styers, M. L., Newell-Litwa, K. A., Doucette, M. M., Wainer, B. H., Falcon-Perez, J. M., Dell’Angelica, E. C., Peden, A. A., Werner, E., Faundez, V.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2006
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1556383/
https://ncbi.nlm.nih.gov/pubmed/16760431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-02-0103
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