Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM

Individuals with systemic lupus erythematosus and rheumatoid arthritis are characterized by the presence of high levels of circulating IgM and IgG autoantibodies. Although IgG autoantibodies often are pathogenic, the role of IgM autoantibodies in autoimmune disease is not clear. Using mice that are...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Boes, Marianne, Schmidt, Tara, Linkemann, Kathrin, Beaudette, Britte C., Marshak-Rothstein, Ann, Chen, Jianzhu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2000
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC15562/
https://ncbi.nlm.nih.gov/pubmed/10655505
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