HIV-1 envelope induces activation of caspase-3 and cleavage of focal adhesion kinase in primary human CD4(+) T cells

Binding of HIV type 1 (HIV-1) envelope glycoproteins to the surface of a CD4(+) T cell transduces intracellular signals through the primary envelope receptor, CD4, and a coreceptor, either CCR5 or CXCR4. Furthermore, envelope–CD4(+) cell interactions increase rates of apoptosis in peripheral blood m...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Cicala, Claudia, Arthos, James, Rubbert, Andrea, Selig, Sara, Wildt, Kathryn, Cohen, Oren J., Fauci, Anthony S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The National Academy of Sciences 2000
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC15560/
https://ncbi.nlm.nih.gov/pubmed/10655504
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