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Influence of aggregate size on the binding and activation of the first component of human complement by soluble IgG aggregates.

The interaction between small aggregates of human IgG and the first component of human complement was studied. Stabilized soluble IgG aggregates of restricted size were prepared by heat aggregation of human IgG, followed by sucrose-density ultracentrifugation. Human C1 was isolated in its precursor...

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Main Authors: Doekes, G, Vanes, L A, Daha, M R
Formato: Artigo
Idioma:Inglês
Publicado: 1982
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1555415/
https://ncbi.nlm.nih.gov/pubmed/7068172
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