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Tolerance and immunity in mice infected with herpes simplex virus: simultaneous induction of protective immunity and tolerance to delayed-type hypersensitivity.

Unresponsiveness to delayed type hypersensitivity was induced in mice following an intravenous injection of herpes simplex virus. The principal tolerogens used were thymidine kinase-deficient virus mutants which grow poorly in vivo; u.v.-inactivated and to a lesser extent formalin-inactivated virus...

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Bibliographic Details
Main Authors: Nash, A A, Gell, P G, Wildy, P
Format: Artigo
Language:Inglês
Published: 1981
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1555179/
https://ncbi.nlm.nih.gov/pubmed/7251047
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