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Inhibition of spontaneous but not antibody-dependent cell-mediated cytotoxicity by simple sugars: evidence that endogenous lectins may mediate spontaneous cell-mediated cytotoxicity.

Using Chang and K-562 cell line cells as targets, we have observed that a number of sugars are capable of inhibiting spontaneous cell-mediated cytotoxicity (SCMC) but not antibody-dependent cell-mediated cytotoxicity (ADCC). The sugars D(-)ribose, beta-gentiobiose, N-acetyl-D-galatosamine, and alpha...

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Detalhes bibliográficos
Main Authors: MacDermott, R P, Kienker, L J, Bertovich, M J, Muchmore, A V
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1555106/
https://ncbi.nlm.nih.gov/pubmed/7275182
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