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Enhanced alternative complement pathway-dependent degradation of soluble immunoglobulin aggregates by macrophages.

The role of complement in the processing of soluble immune aggregates by guinea-pig peritoneal macrophages was studied in a homologous system in vitro. Stable soluble aggregates of guinea-pig IgG1 are shown to activate the alternative pathway in C4-deficient guinea-pig serum. At 37 degrees and under...

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Detalhes bibliográficos
Main Authors: Daha, M R, Van Es, L A
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1555056/
https://ncbi.nlm.nih.gov/pubmed/7251062
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