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Expression of glutamic acid decarboxylase (GAD) in the alpha, beta and delta cells of normal and diabetic pancreas: implications for the pathogenesis of type I diabetes.
One of the paradoxes of insulin-dependent diabetes mellitus is that the destruction of the pancreatic islets' endocrine cells is restricted to the insulin-producing beta cells, whereas the main autoantibodies, islet cell antibodies (ICA), are directed against all endocrine islet cells. GAD has...
Tallennettuna:
Päätekijät: | , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
1993
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1554778/ https://ncbi.nlm.nih.gov/pubmed/8513574 |
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