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Cytochrome P450IID6 recognized by LKM1 antibody is not exposed on the surface of hepatocytes.

LKM1 autoantibody, directed against P450IID6, is accepted as a marker of a particular type of autoimmune hepatitis, but its role in the pathogenesis of the disease is controversial. Localization of P450IID6 on the cell surface of rat hepatocytes was previously reported, suggesting that membrane-boun...

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Detalles Bibliográficos
Main Authors: Yamamoto, A M, Mura, C, De Lemos-Chiarandini, C, Krishnamoorthy, R, Alvarez, F
Formato: Artigo
Idioma:Inglês
Publicado: 1993
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1554760/
https://ncbi.nlm.nih.gov/pubmed/7685669
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