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Asp57-negative HLA DQ beta chain and DQA1*0501 allele are essential for the onset of DQw2-positive and DQw2-negative coeliac disease.

The genetic predisposition to coeliac disease is associated with the HLA DQw2 allele. Coeliac patients lacking the DQw2 allele are very rare and always exhibit the DR4-DQw3 haplotype. We performed oligotyping of polymerase chain reaction (PCR)-amplified DQA1 and DQB1 genes in six DQw2-negative and 3...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Mantovani, V, Corazza, G R, Bragliani, M, Frisoni, M, Zaniboni, M G, Gasbarrini, G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1993
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1554651/
https://ncbi.nlm.nih.gov/pubmed/8419077
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