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Selection of a muramyl peptide based on its lack of activation of nuclear factor-kappa B as a potential adjuvant for AIDS vaccines.

Activation of the cellular transcription factor nuclear factor-kappa B (NF-kappa B) by cytokines and other immunostimulants has been tightly linked with enhanced replication of human immunodeficiency virus-type 1 (HIV-1) in infected cells. Various immunomodulators are currently being examined in ani...

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Détails bibliographiques
Auteurs principaux: Schreck, R, Bevec, D, Dukor, P, Baeuerle, P A, Chedid, L, Bahr, G M
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1554598/
https://ncbi.nlm.nih.gov/pubmed/1424273
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