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A human monoclonal autoantibody to a nucleolar structure.

Peripheral blood lymphocytes from a scleroderma patient (CDC) were isolated, transformed with Epstein-Barr virus and fused to the heteromyeloma SHM-D33. Supernatants from cultures were screened for autoantibody production against nucleoprotamine by ELISA. Positive wells were cloned by limiting dilut...

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Main Authors: Gonzalez, M F, Wichmann, I, Yelamos, J, Melero, J, Magariño, R, Sanchez-Roman, J, Nuñez-Roldan, A, Sanchez, B
Formato: Artigo
Idioma:Inglês
Publicado: 1992
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1554286/
https://ncbi.nlm.nih.gov/pubmed/1572098
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