Acute rejection in heart transplant patients is associated with the presence of committed donor-specific cytotoxic lymphocytes in the graft but not in the blood.

In vivo-activated, committed donor-specific cytotoxic lymphocytes (cCTL) can be propagated and expanded from endomyocardial biopsies (EMB) in IL-2-enriched medium especially during an acute rejection episode. We report here our efforts to detect these cCTL by the same technique in peripheral blood a...

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Detalhes bibliográficos
Main Authors: Vaessen, L M, Baan, C C, Ouwehand, A J, Jutte, N H, Balk, A H, Mochtar, B, Claas, F H, Weimar, W
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1554283/
https://ncbi.nlm.nih.gov/pubmed/1572086
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