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In vivo activation of complement by IgA in a rat model.

In this study we investigated the capacity of rat IgA to activate complement (C) in vivo in a rat model. Rat monomeric (m-), dimeric (d-) and polymeric (p-) IgA MoAbs were injected intravenously and assessed for deposition of C3 and C4 on IgA. By ELISA it was shown that both d- and p-IgA bound C3 wh...

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Autors principals: Stad, R K, Bogers, W M, Thoomes-van der Sluys, M E, Van Es, L A, Daha, M R
Format: Artigo
Idioma:Inglês
Publicat: 1992
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1554236/
https://ncbi.nlm.nih.gov/pubmed/1733628
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