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Surface charge distribution is a determinant of antigen deposition in the renal glomerulus: studies employing 'charge-hybrid' molecules.

The deposition of antigens and immune complexes (IC) in the renal glomerulus is charge-dependent. The demonstration that molecules of net anionic charge, but with discrete positively charged regions, exhibit affinity for the glomerular basement membrane (GBM) extends this concept. Charge hybrid (pol...

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Bibliografiske detaljer
Main Authors: Batsford, S R, Mihatsch, M J, Rawiel, M, Schmiedeke, T M, Vogt, A
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1554210/
https://ncbi.nlm.nih.gov/pubmed/1747955
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