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Surface charge distribution is a determinant of antigen deposition in the renal glomerulus: studies employing 'charge-hybrid' molecules.
The deposition of antigens and immune complexes (IC) in the renal glomerulus is charge-dependent. The demonstration that molecules of net anionic charge, but with discrete positively charged regions, exhibit affinity for the glomerular basement membrane (GBM) extends this concept. Charge hybrid (pol...
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Huvudupphovsmän: | , , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
1991
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1554210/ https://ncbi.nlm.nih.gov/pubmed/1747955 |
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