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Activities of immunosuppressive agents in vitro. II. Different timing of azathioprine and methotrexate in inhibition and stimulation of mixed lymphocyte reaction

Azathioprine (AZ) and Methotrexate (MTX) inhibit thymidine incorporation in mixed lymphocyte reaction (MLR) at non-cytotoxic concentrations. AZ is active only when introduced in the culture during the first 24 hr, whereas MTX is still active when introduced at day 4. These data indicate that AZ migh...

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Detalhes bibliográficos
Main Authors: Bach, Marie-Anne, Bach, J.-F.
Formato: Artigo
Idioma:Inglês
Publicado em: 1972
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1553678/
https://ncbi.nlm.nih.gov/pubmed/5038773
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