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Dynamics of global histone acetylation and deacetylation in vivo: rapid restoration of normal histone acetylation status upon removal of activators and repressors

DNA-binding activators and repressors recruit histone acetylases and deacetylases to promoters, thereby generating localized domains of modified histones that influence transcriptional activity. At the end of a transcriptional response, alterations in histone acetylation status are reversed, but the...

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Detalhes bibliográficos
Main Authors: Katan-Khaykovich, Yael, Struhl, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155357/
https://ncbi.nlm.nih.gov/pubmed/11914279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.967302
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