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Cyclosporin A (CsA) modulates the glomerular production of inflammatory mediators and proteoglycans in experimental nephrosis.

Nephrosis is characterized by glomerular epithelial cell injury and a decrease in the glomerular basement membrane (GBM) proteoglycan content. Although CsA is a useful treatment for a group of patients with this disease, its mechanism of action is unclear. We have previously shown that in experiment...

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Autors principals: Bustos, C, González-Cuadrado, S, Ruiz-Ortega, M, Gómez-Guerrero, C, González, E, Plaza, J J, Egido, J
Format: Artigo
Idioma:Inglês
Publicat: 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1553369/
https://ncbi.nlm.nih.gov/pubmed/8536380
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