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Progressive renal lesions induced by administration of monoclonal antibody 1-22-3 to unilaterally nephrectomized rats.

A new animal model of progressive glomerulosclerosis was developed by administering a single i.v., injection of MoAb 1-22-3 to unilaterally nephrectomized rats. Renal morphological analysis revealed that glomerular lesions characterized by mesangial cell proliferation and mesangial matrix expansion...

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Bibliografiske detaljer
Main Authors: Cheng, Q L, Orikasa, M, Morioka, T, Kawachi, H, Chen, X M, Oite, T, Shimizu, F
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1553319/
https://ncbi.nlm.nih.gov/pubmed/7554387
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